ODCs

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1 OMIM reference -
2 associated genes
10 signs/symptoms

COMMON GENES: 1
PROTEIN INTERACTIONS: 1
COMMON SIGNS: 2

1 OMIM reference -
1 associated gene
4 signs/symptoms

Epidermolysis bullosa simplex with mottled pigmentation

Epidermolysis bullosa simplex with circinate migratory erythema

KRT14	(UniProt - OMIM)		KRT5	(UniProt - OMIM)
KRT5	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	KRT14	(0.69)	KRT5

Citations in the biomedical literature:

Epidermolysis bullosa simplex with mottled pigmentation		Epidermolysis bullosa simplex with circinate migratory erythema
	Synonym(s): - EBS-MP		Synonym(s): - EBS-migr

	Classification (Orphanet): - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare genetic disease - Rare skin disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - 1 MeSH reference: C535959		External references: 1 OMIM reference - No MeSH references


COMMON SIGNS	- Abnormal pigmentary skin changes / skin pigmentation anomalies - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment

Epidermolysis bullosa simplex with mottled pigmentation		Epidermolysis bullosa simplex with circinate migratory erythema
	Very frequent - Autosomal dominant inheritance - Follicular / erythematous / edematous papules / milium - Irregular / patchy skin hypopigmentation Frequent - Abnormal fingernails - Bruisability - Nails anomalies - Palmoplantar hyperkeratosis / keratoderma - Premature ageing		Very frequent - Cutaneous rash - Erythema / erythematous lesions / erythroderma / polymorphous erythema